Intrathecal baclofen therapy

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منابع مشابه

[Intrathecal baclofen therapy for hereditary spastic paraplegia].

Intrathecal baclofen therapy (ITB) is an established treatment for intractable spasticity. More than 1,100 patients have undergone ITB in Japan, and there are about 50 hereditary spastic paraplegia (HSP) The features of ITB in HSP are 1. small doses of baclofen may often be enough, 2. small changes of doses later the symptoms remarkably, 3. doses can be decreased after long term ITB.

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Cerebellar ataxia and intrathecal baclofen therapy: Focus on patients´ experiences

Elucidating patients´ experiences of living with chronic progressive hereditary ataxia and the symptomatic treatment with intrathecal baclofen (ITB) is the objective of the current study. A multicenter qualitative study with four patients included due to the rare combination of hereditary ataxia and ITB therapy was designed to elucidate participants' experiences through semi-structured intervie...

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Best Practices for Intrathecal Baclofen Therapy: Patient Selection.

INTRODUCTION When spasticity interferes with comfort, function, activities of daily living, mobility, positioning, or caregiver assistance, patients should be considered for intrathecal baclofen (ITB) therapy. METHODS An expert panel consulted on best practices. RESULTS ITB can be considered for problematic spasticity involving muscles/muscle groups during all phases of diseases, including ...

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Life-threatening constipation induced by intrathecal baclofen therapy.

drugs (4 azathioprine, 2 methotrexate, 1 interferon beta-1b, 8 gabapentin, 2 pregabalin, 2 phenobarbital, 2 paroxetine, 1 citalopram, 1 venlafaxine, 7 furosemide, 4 heparin, 1 risperidone and 1 olanzapine). Fifteen patients did not receive any concomitant medication. ITB was administered with a mean effective daily dose of 251.3 8 11 g (range 90–580 g). Adverse events of ITB were monitored by e...

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Intrathecal baclofen in severe spasticity

Aim. To present the principles and applications ofintrathecal bac/o/en treatmentfor spasticity of various origin. Review. Intrathecal bac/o/en (ITB) introduced for thefirst time in 1984, is widely used in the treatment 0/ severe spasticity ofvarious origin. Bac/ofen is delivered via an intrathecal catheterji'om an implantable pump that allows to control the dosage over many years. Numerous repo...

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ژورنال

عنوان ژورنال: Rinsho Shinkeigaku

سال: 2010

ISSN: 0009-918X,1882-0654

DOI: 10.5692/clinicalneurol.50.816